Furthermore, the 24 h brain concentration of lithium after lithium orotate was approximately three times greater than that after lithium carbonate. Suggested Use: Not to be taken by pregnant and lactating women. simple chemical salt – just like lithium carbonate or lithium citrate Lithium Orotate 5 mg (250 Capsules) Memory Supplement for Brain & Mood Support - Chelated Lithium Mood Enhancer Memory Pills for Brain - Gluten free, Dairy free, Soy free. Over-the-counter lithium orotate is promoted as a health supplement for use as a low-dose source of lithium; however, very limited clinical evidence exists to support use. Lithium Orotate should not be used if you are dealing with significant renal or cardiovascular disease, severe dehydration or sodium depletion, or if you’re taking diuretics or ACE inhibitors. FREE Shipping on orders over $25 shipped by Amazon. Clinical trials involving 150 mg daily doses of lithium orotate administered 4 to 5 times a week, showed a reduction of manic and depressive symptoms in bipolar patients [50]. Sartori HE, Lithium orotate in the treatment of alcoholism and related conditions, Alcohol 1986 Mar; 3 (2): 97-100. It is helpful in making the highs and lows less as research suggests lithium works to reduce mood swings and enhance feelings of well-being, when taken regularly. These data suggest the possibility that lower doses of lithium orotate than lithium carbonate may achieve therapeutic brain lithium concentrations and relatively stable serum concentrations. Major medical research has not been conducted on lithium orotate since the 1980s due to its patent status and the abundant availability of lithium carbonate. We use data about you for a number of purposes explained in the links below. 5.0 out of 5 stars 1. They are also sometimes used to treat depression and mania. This, along with L-theanine, has greatly reduced my anxiety, depression, agitation, repetitive thoughts and helps me sleep. [5] This study was refuted a year later by another study that repeated the experiment and found that the higher concentrations in the brain could be possibly accounted for by decreased renal function in rats treated with lithium orotate. Please re-enable javascript to access full functionality. Books Advanced Search Amazon Charts Best Sellers & more Top New Releases Deals in Books School Books Textbooks Books Outlet Children's Books Calendars & Diaries Advanced Wondering if it will have any affect on DP. H2O. Smith DF, Schou M. Kidney function and lithium concentrations of rats given an injection of lithium orotate or lithium carbonate. [10][11][12], Orotic acid can be mutagenic in very high doses of 50 mg/kg in mammalian somatic cells. Lithium orotate has the ability to potentially improve cognitive function, enhance mood, and increase bone strength. Online shopping from a great selection at Books Store. Lithium is classified as an essential nutrient, and some of its salts are naturally found in food and drinking water. 0 m equiv kg−1 lithium carbonate, two‐thirds of the 2 h serum lithium concentration was present 24 h after lithium orotate. What have you got to lose? As previously stated, lithium intake appears to be effective even at low doses, and this may account for lithium orotates claimed effectiveness. A friend of mine mentioned her anxiety has vanished since she began taking it daily, and recommended it to me. Some of the reviews on Amazon mentioned it helping Bipolar Disorder and other mental illnesses (though Im always suspicious of Amazon reviews). Only thing I have issues with are hand shakes and slight tremors in the morning. Lithium-orotate is the alternative non-prescription form of lithium I use both personally and prescribe in my practice. I think they are one in the same though, somehow. Lithium alternatives may offer a better option for addressing mood swings than you may have been presented before. You often see it suggested online that lithium-orotate is better absorbed from the intestines than lithium-carbonate but in fact there appears to be little difference in this regard. Lithium is taken by mouth. Lithium orotate is an elemental substance that is also an essential micronutrient. Give it a shot. Lithium calms mania and mood swings by decreasing the sensitivity of norepinephrine receptors. When taken in low doses and in the right form, it's an amazing supplement that can help us all feel a whole lot better!! There are two forms of lithium available to consumers: there is a natural form of the metal/mineral (lithium orotate), considered to have neuroprotective characteristics. I can make better long-term decisions and I'm more optimistic about the future. In these disorders, it reduces the risk of suicide. It has also been known to be used to manage depression, mental health issues, and alcoholism.Let us look at the benefits in detail. In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium ions. Several functions may not work. Disclaimer: I am in no way, shape or form associated with Lithium Orotate or any company that deals with it in any way. edit: I got some, going to try 5mg daily for month or two and I guess I'll report … Lithium is an element. Lithium’s Mechanism of Action: An Illustrated Review, This is not recommended for shared computers. It did give me diarrhea. Lithium orotate — known by the names lithium carbonate, lithium citrate and simply lithium — is a compound used to treat a number of neurological conditions 1. My certainty of life is better. Relentless Improvement Lithium Orotate is well priced and it works. There was a woman on 120mg of lithium orotate who went toxic after 22 days (just read the article earlier today, sorry lost the link, I was doing personal research, as I am asking myself the same question about orotate, and having difficulties finding the answers I need). J Pharm Pharmacol 1979;31:161-3.. View abstract. As for libido, may have enhanced it a bit and thats coming from having no libido at all for quite some time. I started lithium a few weeks ago I think. Although lithium orotate is considered safer than other lithium-based compounds, there are still a number of side effects, drug interactions and potentially serious conditions that can result from regular lithium orotate use 1 3. Lithium salts are chemical salts of lithium used mainly in the treatment of bipolar disorder as mood stabilizers. A healthy individual can benefit from taking as little as one milligram, while a depressed patient needs 20 to 30 milligrams a day, split into several doses. Whatever version that requires a prescription. [13] It is also mutagenic for bacteria and yeast. Lithium (especially Lithium Orotate) really is the misunderstood mineral! What Does Lithium Orotate Do to the Brain? Noncontrolled studies have examined the use of low-dose lithium orotate in the treatment of alcoholism, migraines, and depression associated with bipolar disorder. $24.99 $ 24. It is possible that certain formats are more effective and/or safer than others in the specific domain of anxiety disorders. By continuing to browse our site you agree to our use of data and cookies. The Benefits of Lithium Orotate. Typical dosages of lithium orotate range from 30 mg – 800 mg per day. [7][8][9], Lithium orotate's safety remains in question. Lithium Orotate seems to come in 120mg capsules, most often, but it's confusing because people often say they only take 5 to 10 mg daily. Lithium orotate (lithium bound with a natural chemical called orotic acid, found in breast milk 7 and certain root vegetables, available as a supplement without a prescription) There have been many other compounds/mixtures produced over the last century and a half. The orotate form of lithium is used by doctors to help stabilize and equilibrate mood. Not to be taken in conjunction with SSRIs or MAOIs unless advised by a health professional. Mechanism unknown according to google. [14], InChI=1S/C5H4N2O4.Li/c8-3-1-2(4(9)10)6-5(11)7-3;/h1H,(H,9,10)(H2,6,7,8,11);/q;+1/p-1, "The clinical applications of lithium orotate. I don't think it had any beneficial effect. The higher dosages are usually broken up into 3 dosages per day and are most often for those with bipolar or manic disorders, those recovering from alcoholism, or some of the other disorders listed in ‘ Conditions that Lithium May Help ’. Lithium orotate dosage depends on the condition that is being treated. Concerns have been raised in medical literature after a case report of a patient who required medical attention after taking an overdose of lithium orotate supplement. In this compound, lithium is non-covalently bound to an orotate ion, rather than to a carbonate or other ion, and like other salts, dissociates in solution to produce free lithium … Medical doctors prescribe lithium carbonate for the management of bipolar disorder and as an adjunct for major depression, however, lithium orotate and lithium aspartate can be purchased online from supplement companies. Lithium Orotate - posted in Treatment Options: Wondering if anybody out there has experience with this supplement. You currently have javascript disabled. Lithium (orotate) - Pure Prescriptions. Wondering if anybody out there has experience with this supplement. It’s a member of the alkali earth metals family of elements which puts it in the same class as such minerals as sodium and potassium. There are a lot of brands on Amazon, ranging from 5mg to 120mg, so it's really confusing which one to buy, and I can't find much research on the internet about it. Please Read the Community Forum Guidelines Before Posting. Because of the superior bioavailability of lithium orotate, the therapeutic dosage is much less than prescription forms of lithium. Brand I 've tried lithium after lithium carbonate, two‐thirds of the 2 serum... Therapeutic dosage is much less than prescription forms of lithium after lithium orotate is an elemental that!, repetitive thoughts and helps me sleep is also mutagenic for bacteria and yeast also known as salts. This, along with L-theanine, has greatly reduced my anxiety, depression, agitation, repetitive thoughts and me. Orotates claimed effectiveness this is not recommended for shared computers per day tremors. Has really helped with slowing my cognitions down to a good level the... 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